Treatment of Kimura disease with mycophenolate mofetil monotherapy

ALHE: angiolymphoid hyperplasia with eosinophilia KD: Kimura disease MMF: mycophenolate mofetil INTRODUCTION Kimura disease (KD) is a rare idiopathic condition that presents as solitary or multiple painless subcutaneous masses in the head and neck region. It may also involve extracutaneous sites, such as regional lymph nodes, major salivary glands, and the kidneys. Most cases reported occurred in Asian men between 20 and 30 years of age. Treatment is often sought for symptomatic relief and cosmetic concerns. Therapeutic modalities for KD include surgical excision, radiotherapy, and various immunomodulating agents, such as oral corticosteroids, cyclosporine, and leflunomide. Most cases have favorable initial responses to treatment, but relapse occurs at rates as high as 60% to 100%. We report a case of KD with sustained response to mycophenolate mofetil (MMF) monotherapy.